Our lifestyle hotel welcomes you to iconic Milan

Welcome to the Exceptional in Milan. Our 5-star hotel pampers the senses in true Italian fashion, prioritizing flavors, sights, and comfort. Select your preferred home away from home from our 159 rooms and suites. Enjoy a bite from one of our spacious restaurants—ISSEI boasts a fusion of Asian and Peruvian cuisine along with a bird's-eye-view from the rooftop. After sightseeing, the complimentary fitness center is an excellent place to unwind and keep up with your health goals. Radisson Collection Hotel, Santa Sofia Milan, places you in an exciting neighborhood by entertainment, squares, and minutes from the city's main attractions.

Savor stylish spaces and contemporary comfort in Milan

Radisson Collection Hotel, Santa Sofia Milan, boasts 159 newly renovated rooms and suites in an exciting urban neighborhood. Designed for comfort and style, our rooms include soft bathrobes with slippers, espresso machines, and our Collection bathroom amenities.
  •  23 m²
  • 1 king or 1 queen or 2 twin
  • 2 adults
Enjoy an excellent night's sleep and a relaxing morning in the Collection Room.
  •  27 m²
  • 1 king or 1 queen or 2 twin
  • 2 adults
Unwind in superb comfort with your choice of bed type in the Collection Superior Room.
  •  33 m²
  • 1 king or 1 queen
  • 2 adults
Upgrade to a Collection Premium Room for extra space, in addition to the standard amenities.
  •  38 m²
  • 1 king
  • 2 adults
Book an elegant Junior Suite for more space and comfort.
  •  41 m²
  • 1 king
  • 2 adults
Luxuriate in the stylish Suite with separate sleeping and living spaces.
  •  46 m²
  • 1 king or 1 queen or 2 twin
  • 4 adults
Stay closer to loved ones by booking the Family Stay - 2 Connected Rooms.
Discover our three dining venues. For a social spot to meet friends or colleagues while indulging in a unique blend of American, Milanese, and Mediterranean flavors, make your way to Sofia Kitchen & Bar on the ground floor. In the evening, our rooftop restaurant ISSEI, boasts spectacular views. We also offer snacks at our 4th floor bar by the outdoor pool.

Milan is famous for fashion, art, cuisine, and history. Stay close to it all at our remarkable Collection hotel. Enjoy a scenic walk to the medieval Sforzesco Castle or the Piazza del Duomo and grab a local coffee or indulgent bite to go on your way. For a sophisticated night of theater, Teatro Alla Scala is perfect for a show while gazing at Neoclassical architecture. See more about our top attraction suggestions.

Duomo di Milano

0.58 mi / 0.93 km from the hotel
One of Milan's more easily recognizable landmarks, the Duomo di Milano is a spectacular monument that should be on every sightseeing itinerary. Don't forget to take pictures in front of this Gothic and Renaissance masterpiece, which took about six centuries to complete.

Via Montenapoleone

0.87 mi / 1.4 km from the hotel
Whether planning a shopping spree or wishing to see what gives Milan its fashion-forward reputation, make sure to visit Via Montenapoleone. Don’t forget your camera – this high-end shopping district hints back at the 19th century, when it was a preferred neighborhood for the city's top aristocratic families.

Teatro alla Scala

0.78 mi / 1.26 km from the hotel
One of the world’s renowned Opera houses, the Teatro alla Scala is a must-see when visiting Milan. The neighborhood surrounding the Opera House is also filled with lovely squares and museums.

Castello Sforzesco

1.07 mi / 1.72 km from the hotel
A scenic walk through Milan’s enchanting streets will lead you to this 14th-century fortification. For a time, the Castello Sforzesco also served as one of Milan’s grander residences. Today, visitors will find a variety of cultural museum exhibits.


0.55 mi / 0.89 km from the hotel
End a fun-filled day in Milan with a walk along the Navigli, the city’s landmark-lined canal system. During the day, visit the art galleries that are embedded within the side streets of Navigli Grande, or start your evening with an aperitivo or cocktail at one of the many canalside terraces.

Pinacoteca di Brera

1.1 mi / 1.77 km from the hotel
Discover one of the greatest art collections in the world at the Pinacoteca di Brera. A true treat for art and history-lovers, the gallery hosts numerous masterpieces in Italian art history. Afterward, exploring the neighborhood, surrounded by lovely, smaller art galleries, shops, bars, and restaurants.
Via Santa Sofia, 37, Milan 20122, Italy

Our city center hotel is easy to reach by taxi, train, and when driving yourself. The mesmerizing Milano Centrale Railway Station is a 15-minute drive away.

From Milan Linate Airport (LIN)

By taxi or car:

The trip from the airport to the hotel takes approximately 20 to 30 minutes, depending on traffic.

From Milano Centrale Railway Station

By taxi or car:

Hail a taxi or drive to reach the railway station from our hotel within 15 minutes.